?Noel
Noel發(fā)音
英：[n???el] 美：[no??el]
英： 美：
Noel中文意思翻譯
n. 尤用於圣誕頌歌中）圣誕節(jié)
n. 諾埃爾(姓氏；男子名；女子名)
Noel常見例句
1 、A caring attitude can not only save you a small fortune, but also even make you feel good about being tight-fisted and offering more care than presents.--O,Hare Noel, American writer───關(guān)心的態(tài)度不僅能幫你省下一筆可觀的錢,而且甚至能使你感到一份欣慰,因為你花錢不多并且給予了勝過禮物的關(guān)懷。美國作家諾埃爾
2 、Noel's dead, but somebody else is out there.─── 諾埃爾死了 但還有人沒被抓住
3 、George Noel Gordon | Lord Byron [England]───拜倫[英
4 、At the end of October, Tropical Storm Noel created a major disaster in the Dominican Republic.───十月底的諾艾風暴在多明尼加釀成嚴重災(zāi)情，中部波那省的白石地區(qū)是最嚴重的災(zāi)區(qū)之一；
5 、Using a noel method to rank genes, they found that XOR was at the top of the list of genes that fit the profile of a fat generator.───他們使用一種新方法將基因分類，發(fā)現(xiàn)XOR在基因目錄的頂端，這符合對脂肪驅(qū)動因子的描述。
6 、Adances in molecular biology technology allow DNA to be easily manipulated and make the implementation of noel DNA accine strategies possible.───先進的分子生物學技術(shù)使得DNA容易被操縱,也使得實現(xiàn)新的DNA疫苗策略成為可能.
7 、Noel isn't the only one we have to worry about.─── 諾埃爾不是唯一需要擔心的
8 、David Noel───大衛(wèi)·諾爾
9 、"Our analysis reealed potential mechanisms of irulence, which we hope will help us deelop noel antiiral strategies to both outwit the irus and moderate the host immune response.───我們分析發(fā)現(xiàn)了病毒毒力的來源，有助于發(fā)展對付病毒以及降低宿主免疫反應(yīng)的新型抗病毒藥物?！?/p>
10 、This noel correlation between thermal and cellular measurements in asthma suggests that both of these noninasie indices are sensitie to the degree of underlying chronic airway inflammation.───在哮喘患者熱量和細胞測量之間，這種新穎的相互關(guān)系表明：這兩個非侵入性的指標對潛在的慢性導氣管炎癥程度是敏感的。
11 、Product: Cacao Noel Fondue au Chocolat Pouch Supplier: LPS Industries The Cacao Noel Fondue au Chocolat Pouch entices the consumer with the promise of gourmet taste with minimal preparation.───產(chǎn)品：可可諾埃太子港火鍋巧克力袋 供應(yīng)商：脂多糖產(chǎn)業(yè) 諾埃爾的可可巧克力芝士火鍋太子港袋引誘消費者的承諾，美食品嘗以最少的準備工作。
12 、As a modern parent, I know that it's not how much you give children those counts, it's the love and attention you shower on them.--O,Hare Noel, American writer───作為一個現(xiàn)代的父母,我很清楚重要的不是你給了孩子們多少物質(zhì)的東西,而是你傾注在他們身上的關(guān)心和愛。美國作家諾埃爾
13 、"Brian Barwick has been fantastic, the committee behind the chairman, Dave Richards and Noel White gave me tremendous support after the bad night in Andorra.───“布萊恩.巴威克很棒，總裁下屬的委員會，戴維.里查德茲以及諾埃爾懷特都在安道爾那個糟糕的夜晚后給我了巨大的幫助?！?/p>
14 、"Clearly, we need much more information about the biological role of this protein prior to generating noel therapies for pre-eclampsia based around reducing its effects," he concluded.───他補充說:在受孕最初幾周**形成時所發(fā)生的一系列事件會導致一些不良妊娠結(jié)局如重度先兆子癇及死產(chǎn)等,這些事件可能在孕婦第一次產(chǎn)前檢查之前就已經(jīng)開始了.
15 、Noel pushed a girl down a flight of stairs and tormented us in the dollhouse.─── 諾埃爾把一個女孩從樓梯上推了下來 還把我們困在玩具屋里折磨我們
16 、Was twice nominated for Broadway's Tony Award as Best Actor (Play): in 1987 for "Les Liaisons Dangereuses," and in 2002 for a revival of Noel Coward's "Private Lives."───2次獲百老匯托尼獎戲劇類最佳男演員提名，1987年的“危險關(guān)系”和2002年再版的“私生活”；
17 、SNPs in fie noel independent loci exhibited strong and consistent eidence of association with breast cancer (P ───五個新的獨立位點中的SNP表現(xiàn)出與乳腺癌明顯相關(guān)性(P
18 、Noel Barrie Hooper───何柏(1931-),英國人,曾任香港法官。
19 、Noel Bruynooghe sunk the decisive 9-ball as he and partner Serge Das leapt in delight as they had recorded one of the biggest shocks ever in world pool.───最后的9號球由諾歐打進。終場9比6取得勝利，終結(jié)了夢幻臺灣隊！諾歐和沙吉雀躍萬分，無比興奮。他們知道，比利時隊或許已經(jīng)寫下了世界撞壇最驚人的一筆歷史紀錄！
20 、George Noel Gordon───拜倫[英]
21 、Officials in the Dominican Republic say at least eight people have died in the fierce thunderstorms and flooding brought by Tropical Storm Noel.───多米尼加共和國**聲稱在這次由諾爾熱帶風暴引起的猛烈的雷暴雨和洪災(zāi)中至少8人死亡，3人失蹤。
22 、"The Neanderthal monobrow, famously displayed by Noel Gallagher, will soon be ancient history as alpha males look to cultivate dark, strong brows with the help of threading and dying.───像諾埃爾?加拉格爾（譯者注：英國“綠洲樂隊”成員）那樣很像原始人的一字眉很快將成為歷史，男人們開始希望通過絞眉或染眉打造出又濃又粗的眉毛。
23 、Noel Koch recently left his Pentagon office toting an overnight bag and rode to Washington's National Airport.───埃爾·科克最近曾攜帶一只輕便旅行袋，離開國防部五角大樓辦公室，駕車前往華盛頓機
24 、We play cards, we drink a little beer, we have fun with the noels.─── 我們打打牌 喝喝啤酒 和諾埃爾姐妹花一起找點樂子
25 、Despite the two and a half hour drive from Santo Domingo to Bombita in Barahona province, volunteers greet Tropical Storm Noel victims with the brightest smiles as soon as they get off the bus, hoping to cheer them up.───盡管開車從首都圣多明尼哥，到巴拉歐納省的蒙必達地區(qū)，需兩個半小時的車程，志工一下車看到諾艾風災(zāi)的受災(zāi)戶，立即展露笑容，給災(zāi)民最大的鼓勵。
26 、Julian played "The First Noel", and other favorites.───朱利安又演奏了“第一圣誕頌歌”以及幾首最受歡迎的樂曲。
27 、AshleyMadison’s boss, Noel Biderman, thinks his site, andothers, are prospering for another reason: money problems.───他說：“大部分婚姻關(guān)系的不和來自于經(jīng)濟糾紛?！?/p>
28 、In an exclusive interview with SFTW, Liam, Noel, Gem and Andy answer what you wanted to know.───在這次聯(lián)合將回答你所想知道的。
29 、Noel approchant,les ventes sur Internet explosent.───圣誕節(jié)臨近，因特網(wǎng)上商品銷售火爆。
30 、The first multiprotocol routers were independently created by staff researchers at MIT and Stanford in 1981;the Stanford router was done by William Yeager, and the MIT one by Noel Chiappa;───多協(xié)議路由器的第一個獨立的科研人員創(chuàng)建的麻省理工學院和斯坦福大學在1981年，斯坦福路由器是由威廉克耶格爾，以及麻省理工學院的一個諾埃Chiappa ;
31 、But the region is still bracing for heavy rains from Tropical Storm Noel.───但是該地區(qū)仍舊做好準備以對付熱帶風暴“諾埃爾”所帶來的強降雨。
32 、Noel's mom was gonna take us for pizza.─── 諾埃爾的媽媽要帶我們?nèi)コ耘_
33 、The Teessiders ran out 2-0 winners that day thanks to goals from Noel Whelan and Andy Campbell.───主隊憑借NoelWhelan和AndyCampbell的進球2比0取勝。
34 、Noel: Ok well, I'll stop interviewing you now and you can interview me.───好吧我不再采訪你了你可以采訪我了。
35 、Cain and Abel, Linus and Lucy, Liam and Noel.───例如，該隱和亞伯[1]，萊納斯與露西[2]，連恩與諾爾[3]。
36 、The new genes do not immediately suggest any new therapy, but point to a noel biological basis for the disease, from which effectie treatments could emerge in time.───新基因不會直接給出新治療方法，但是會對疾病的生物學基礎(chǔ)有新的基本認識，那么由此引出有效的治療措施也將指日可待。
37 、Noel: That all my songs and the rest are quite average.───我的歌最好其他的都很一般。
38 、The identification of noel cell-type specific markers may lead to a better understanding of cell-type specific functions in the normal brain as well as in diseases in which particular brain cell types are dysfunctional.───對新細胞型特異性標記的識別能幫助人們更好的理解健康人腦中細胞類型的特異性功能，從而與病腦或功能失調(diào)的的特殊大腦細胞型相區(qū)別。
39 、LIAM once said he was John Lennon reincarnated. So who does he think Noel could be?───曾經(jīng)說過他是約翰列儂二世。
40 、Brazil Father Christmas is called Papai Noel .───巴西圣誕老人被叫做“圣誕阿爸”。
41 、Credits Lyrics by Dolores O'Riordan Music by Dolores O'Riordan, Noel Hogan Lyrics If you, if you could return.───如果你,如果你能回來,。
42 、Noel: I would rather kick my daughter out of the house than let her go and support Manchester United.───我寧可把我女兒踢出去也好過看她支持曼聯(lián)。
43 、Was twice nominated for an Laurence Olivier Award as Best Actor (Play): in 1987 for "Les Liaisons Dangereuses," and in 2002 for a revival of Noel Coward's "Private Lives".───2次獲得勞倫斯.奧利弗戲劇獎最佳男演員提名，1987年因為“危險關(guān)系”和2002年因為“私生活”；
44 、Pourquoi les anges ont-ils des ailes? --Pour nous faire croire au Pere Noel.───為什么天使會有翅膀？ --為了讓我們相信有圣誕老人。
45 、Noel: Best song I've every written, I'd probably say, Rock and Roll Star, the most overrated Wonderwall.───你到現(xiàn)在寫的最好的歌是那首？最名不副實的是那首？
46 、A green iguana is seen at the Noel Kempff Mercado Zoo in Santa Cruz, Bolivia, Aug. 17. (Reuters───八月十七日周日，一只綠色的鬣蜥蜴出現(xiàn)在玻利維亞圣克魯茲的諾爾普夫梅爾卡多國家公園。（路透社照片）
47 、His noel was set in 2142.───他的**背景設(shè)定在2142年。
48 、IF Tony Blair told the Queen to give Noel a knighthood as his parting gesture before stepping down, would you accept it?───封為騎士作為你們解散前的表彰,你會接受嗎?
49 、Noel: We didn't have to get involved with any of it but we're never going to do another “best of”.───我們過去沒有必要做這種東西，不過以后也不會再出什么“精選”了。
50 、a reasonably well - constructed duologue for two experienced performers(Noel Coward)───兩位有經(jīng)驗演員表演的組織合理的對白(諾埃爾 科沃德)
51 、Pastor Noel’s children are blessed with a small television that there children need not to go to another house to watch TV.───感謝主，讓拿威傳道的小孩擁有小電視看，而不需要到鄰居家觀看。
52 、Noel: I told Our Kid the band was shit, but he definitely had something as a frontman.───" Noel: 我告訴他（LIAM）樂團（OASIS前身Rain）很屎,但是他確實有主唱的味道。
53 、Noel had the stylist send over a few things for the tour.─── 諾爾讓設(shè)計師送來了幾套巡演服裝
54 、After the failure of his last noel, his reputation stands on slippery grounds.───他的上部**失敗之后，聲譽一落千丈。（不能譯為"站在滑動的場地上了。"
55 、I feel like we're in a Noel Coward play. Someone should be making martinis.───我覺得我們像是在諾埃爾?考沃德的戲劇里。有人應(yīng)該做些馬提尼酒。
56 、Noel Bas───巴斯
57 、Hooper, Noel Barrie───何柏
58 、Beattie GM,Montqomery AM et al.A noel approach to increase human islet cell mass while presering beta-cell function.Diabetes.2002 Dec;51(12):3435-9.───按照研究者的方法,似乎是可以將B細胞體外培養(yǎng)使其增殖并保留原有B細胞的特性啊,但為什么這樣的培養(yǎng)方法沒有廣泛應(yīng)用呢?
59 、Noel Freeman───弗里曼
60 、Noel: The reason the band's stayed together is 'cos it has to, because basically I've got fuck all else. have not got anything else to look forward to.───樂團不解散的原因是它必須這樣,因為基本上我其他什麼都沒興趣。沒任何別的東西可以盼望。
61 、Patients with bipolar disease exhibited hyperactiity and a wide range of exploration when in a noel enironment, according to the researchers.───按照研究人員所說，雙相情感障礙病人在一個新環(huán)境中會表現(xiàn)出高度活躍和一系列的探究行為。
62 、Mr Noel was a whizz at marketing both his family and Mr Madoff's supposed expertise.───在推銷自己的家庭以及馬多夫的所謂操作訣竅方面，諾埃爾是一個專家。
63 、Russia in the Battle of Tsushima[by] Noel F.───書刊名/作者 The Emperor's sword/Japan vs.
64 、"a reasonably well-constructed duologue for two experienced performers" (Noel Coward)───“兩位有經(jīng)驗演員表演的組織合理的對白”(諾埃爾·科沃德)
65 、Noel de Mille───德米爾
66 、Good night my darlings, I'll see you tomorrow. --Noel Cowad, American writer───晚安,親愛的人們,明天再見。
67 、Noel apologized and we got back together.─── 諾埃爾給我道歉了 我們復(fù)合了
68 、Noel, I do not find it difficult to keep my work and my social life separate.─── ?,?e?? 罻????
69 、Monique Noel De Titty Mayor, City of Brossard, Quebec, Canada───加拿大魁北克省布魯薩德市市長
70 、This is the first in io eidence showing that an ACE inhibitor protects human myocardium, possibly ia PC-mimetics actions, a noel property that might explain the cardioprotectie actions of these drugs.───本研究首次在人體試驗中顯示血管緊張素抑制劑的心肌保護效應(yīng)，這類藥物可能是通過擬缺血預(yù)適應(yīng)機制產(chǎn)生心肌保護作用。
71 、DAVI president Francis Noel appointed Dr.Crawford the first chair of the Archives Committee.───二、數(shù)字化網(wǎng)絡(luò)出版的標準化是建設(shè)數(shù)字圖書館的前提。
72 、Allington ;illustrated by Noel Spangler.───作者聲明: by Richard L.
73 、It suggested that the nitrites reaching 900 mg/kg in feeds caused poor performance and had ill-effect on health of ducks. The NOEL of nitrite in formula feed for ducks may be 600 mg/kg.───因此 ,日糧中亞硝酸鹽含量達到 90 0mg kg時 ,肉鴨健康狀況明顯受到不良影響 ,建議飼料中亞硝酸鹽的無明顯作用水平 (NOEL)定為 6 0 0mg kg。
74 、We are working on a noel approach to preent PKB actually binding to the cell membrane.───我們在做的工作就是用一個新途徑來抑制蛋白激酶與細胞膜的結(jié)合?！?/p>
75 、New insights will hopefully pae the way for us to explore noel ways of treating this condition.───新的知識將為我們探索應(yīng)對這種情形的新方法鋪平道路。”
76 、Little Noel Wants to Fly───小諾埃爾想飛
77 、Tutorials in measure theory, lebesgue integration and probability, by Noel Vaillant.───介紹概率論以及測量方法方面的網(wǎng)站。
78 、At the end of October, Tropical Storm Noel created serious flooding in the Dominican Republic, making tens of thousands of people homeless.───十月底，諾艾颶風橫掃多明尼加，在各地造成嚴重水災(zāi)，讓上萬人流離失所。
79 、Noel Pong graduated from The Hong Kong Academy for Performing Arts with First Class Honours in modern dance and joined CCDC in 1997.───龐智筠1997年以一級榮譽畢業(yè)于香港演藝學院舞蹈學院現(xiàn)代舞系，同年加入城市當代舞蹈團。
80 、Noel, I'm so sorry. I got to go to the hospital.─── 諾爾 抱歉 我得去醫(yī)院
81 、Noel: Oh, this is for China though right?───可這是給中國做的采訪對吧？
82 、SNPs in fie noel independent loci exhibited strong and consistent eidence of association with breast cancer (P ───在五種新的獨立的基因位點的單核苷酸多態(tài)性顯出強的一致的證據(jù)與乳腺癌相關(guān)。
83 、Noel's been in the middle of everything that's been happening to us.─── 諾埃爾最近一直 從中作梗 妨害我們
84 、Noel approach to cancer drug gien major boost───新途徑的腫瘤藥物獲得重大支助
85 、This inention relates to fishing bait, and more particularly to a noel composition useful in conjunction with the same as well as the means for aailing of such composition in use.───本發(fā)明是有關(guān)一種垂釣魚餌，更特別地，一種新式成分用于連接類似的，同時對這樣的成分有利。
86 、James Links is a 49-year-old space trucker anxious to return to Earth and reunite with his estranged children Leon and Noel.───他們找到了舊火箭“咻”，與博物館長合力修好后乘火箭沖出太空，但遭到埋伏。
87 、"This emphasizes the need to deelop noel medical strategies based on a comprehensie understanding of the biological mechanisms underlying gliomagenesis.───“這就強調(diào)了發(fā)展新型治療方案的必要性，而這些治療方案需要建立在全面掌握膠質(zhì)瘤形成的生物機制的基礎(chǔ)上。”
88 、Illustrations: Noel Stapleton and Bernard Tate, Sydney───圖案設(shè)計:諾爾·斯泰頗坦和伯納德·泰特,悉尼
89 、Inhibition of early steps of platelet adhesion to the ischemic endothelium and the subendothelial matrix may offer a noel and safe treatment strategy in acute stroke.───在血小板黏附在血管內(nèi)皮細胞及內(nèi)皮下基層的早期進行抑制可能提供一種新的安全的治療缺血性卒中的治療方法。
90 、Pour nous faire croire au Pere Noel.───為了讓我們相信有圣誕老人.
如何計算藥物的PDE？
根據(jù)ICH和EMA發(fā)布的指南，可以通過毒理學數(shù)據(jù)查詢來計算PDE。
歐盟“關(guān)于在共用設(shè)施生產(chǎn)不同藥品的風險識別中使用的基于健康的暴露限度的指南”中提到的PDE計算方法：F1物種之間的差異系數(shù)（大鼠5小鼠12狗2兔子2.5猴子3其他10）F2個體之間差異，固定數(shù)10F3為短期接觸急性毒性研究的可變系數(shù)。固定值為10。但如果試驗周期很長的話，建議參考ICH Q3C中的F3取值。
F4為毒性因子，取值1-10。急性毒性下可能使用，如非遺傳毒性致癌性、神經(jīng)毒性或致畸性；F5為可變因子，當沒有建立無作用水平時可能使用，當只有LOEL時，根據(jù)毒性大小可能使用最大為10的因子。但是NOEL怎么得出，需要毒理學家或者毒理背景的人員，通過綜合評判計算得到。
對于有些化學物質(zhì)，不一定有非常全面的數(shù)據(jù)，就需要通過實驗來提供。
即使是有數(shù)據(jù)庫，面對浩如煙海的文獻，怎么選擇合適的數(shù)據(jù)對于藥廠或者小型藥企來說十分困難，況且藥企也沒有專業(yè)的人員有能力去撰寫PDE的報告。
最好的方法就是委托別的機構(gòu)來寫，或者找GMP咨詢公司來做。
其實最直接的方式，就是買PDE報告。哈哈，可以試試萬能的**有人賣不~
如何評價Noel gallagher在英國現(xiàn)在的地位？
諾埃爾·加拉格出生在曼城。父母都是愛爾蘭人，家里有三個孩子，他是家里的第二個孩子，哥哥Paul出生于1966年，弟弟Liam Gallagher出生于1972年。由于父親酗酒，他們兄弟挨了不少打。他總是活在自己的世界里，所以Liam形容他為“家族怪胎”。父親的這種行為在Noel和Paul身上都留下了烙印——他倆都有些許結(jié)巴。作為長子，Paul理所當然地一個人一間房，這樣，Noel就不得不和Liam共用一間房。1976年，他母親Peggy對丈夫提出分居。六年后，她最終帶著三個孩子離開了這個酗酒的丈夫。
感情
前妻Meg Mathews 1997年6月5日在美國拉斯維加斯的小禮堂結(jié)婚，2000年1月27日生有一女Anais Gallagher ,2001年冬天離婚.
現(xiàn)女友Sara MacDonald 于2007年9月22日生有一子Donovan Rory MacDonald Gallagher